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Index > Protein center > PLA2G1B(Gene name) > Pig
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  • PLA2G1B (Gene name),
  • Phospholipase A2, major isoenzyme (Protein name ),  PA21B_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PLA2G1B;
    Protein name:
    Phospholipase A2, major isoenzyme;
    Alternative:
    Phosphatidylcholine 2-acylhydrolase 1B;Group IB phospholipase A2;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Monomer or homodimer.
    Function:
    PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    146
    Sequence:
    50:
    MKFLVLAVLL | TVGAAQEGIS | SRALWQFRSM | IKCAIPGSHP | LMDFNNYGCY | 
    100:
    CGLGGSGTPV | DELDRCCETH | DNCYRDAKNL | DSCKFLVDNP | YTESYSYSCS | 
    146:
    NTEITCNSKN | NACEAFICNC | DRNAAICFSK | APYNKEHKNL | DTKKYC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    E0576h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    E0576d
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    E0576m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    E0576r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    E0576p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Pig Phospholipase A2, major isoenzyme
    MSDS:
    Please sign in first.
    ELISA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    E0576b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    U0576r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    U0576m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    U0576p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    U0576b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Phospholipase A2, major isoenzyme
    MSDS:
    Please sign in first.
    CLIA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    U0576h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig Phospholipase A2, major isoenzyme
    Cat.:
    U0576d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Cat.:
    P0576Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Cat.:
    P0576Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Polyclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Polyclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Cat.:
    P0576Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Polyclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Monoclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Monoclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Monoclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Monoclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Monoclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Monoclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Monoclonal Antibody for Pig Phospholipase A2, major isoenzyme
    Protein for Pig Phospholipase A2, major isoenzyme
    Protein for Pig Phospholipase A2, major isoenzyme
    Protein for Pig Phospholipase A2, major isoenzyme
    Protein for Pig Phospholipase A2, major isoenzyme
    Protein for Pig Phospholipase A2, major isoenzyme
    Protein for Pig Phospholipase A2, major isoenzyme
    Protein for Pig Phospholipase A2, major isoenzyme

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    References
    1. 1.
      "Expression of porcine pancreatic phospholipase A2. Generation of active enzyme by sequence-specific cleavage of a hybrid protein from Escherichia coli."
      de Geus P. , van den Bergh C.J. , Kuipers O. , Verheij H.M. , Hoekstra W.P.M. , de Haas G.H.
      Nucleic Acids Res.15:3743-3759(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Pancreas.
    2. 2.
      "Pancreatic phospholipase A2: isolation of the human gene and cDNAs from porcine pancreas and human lung."
      Seilhamer J.J. , Randall T.L. , Yamanaka M. , Johnson L.K.
      DNA5:519-527(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Pancreas.
    3. 3.
      "Studies on phospholipase A and its zymogen from porcine pancreas. I. The complete amino acid sequence."
      de Haas G.H. , Slotboom A.J. , Bonsen P.P.M. , van Deenen L.L.M. , Maroux S. , Puigserver A. , Desnuelle P.
      Biochim. Biophys. Acta221:31-53(1970) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 16-146
    4. 4.
      "The primary structure of phospholipase A2 from porcine pancreas. A reinvestigation."
      Puijk W.C. , Verheij H.M. , de Haas G.H.
      Biochim. Biophys. Acta492:254-259(1977) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    5. 5.
      "Studies on phospholipase A and its zymogen from porcine pancreas. II. The assignment of the position of the six disulfide bridges."
      de Haas G.H. , Slotboom A.J. , Bonsen P.P.M. , Nieuwenhuizen W. , van Deenen L.L.M. , Maroux S. , Dlouha V. , Desnuelle P.
      Biochim. Biophys. Acta221:54-61(1970) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS
    6. 6.
      "Dimerization and activation of porcine pancreatic phospholipase A2 via substrate level acylation of lysine 56."
      Tomasselli A.G. , Hui J. , Fisher J. , Zuercher-Neely H. , Reardon H.M. , Oriaku E. , Kezdy F.J. , Heinrikson R.L.
      J. Biol. Chem.264:10041-10047(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT LYS-78
      tissue: Pancreas.
    7. 7.
      "Structure of porcine pancreatic phospholipase A2 at 2.6-A resolution and comparison with bovine phospholipase A2."
      Dijkstra B.W. , Renetseder R. , Kalk K.H. , Hol W.G.J. , Drenth J.
      J. Mol. Biol.168:163-179(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS);ACTIVE SITE;BINDING SITES
    8. 8.
      "Structure of an engineered porcine phospholipase A2 with enhanced activity at 2.1-A resolution. Comparison with the wild-type porcine and Crotalus atrox phospholipase A2."
      Thunnissen M.M.G.M. , Kalk K.H. , Drenth J. , Dijkstra B.W.
      J. Mol. Biol.216:425-439(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS)
    9. 9.
      "X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor."
      Thunnissen M.M.G.M. , Ab E. , Kalk K.H. , Drenth J. , Dijkstra B.W. , Kuipers O.P. , Dijkman R. , de Haas G.H. , Verheij H.M.
      Nature347:689-691(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS)
    10. 10.
      "Porcine pancreatic phospholipase A2: sequence-specific 1H and 15N NMR assignments and secondary structure."
      Dekker N. , Peters A.R. , Slotboom A.J. , Boelens R. , Kaptein R. , de Haas G.H.
      Biochemistry30:3135-3147(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    11. 11.
      "NMR structures of phospholipase A2 reveal conformational changes during interfacial activation."
      van den Berg B. , Tessari M. , Boelens R. , Dijkman R. , de Haas G.H. , Kaptein R. , Verheij H.M.
      Nat. Struct. Biol.2:402-406(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    12. 12.
      "Solution structure of porcine pancreatic phospholipase A2."
      van den Berg B. , Tessari M. , de Haas G.H. , Verheij H.M. , Boelens R. , Kaptein R.
      EMBO J.14:4123-4131(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    13. 13.
      "Solution structure of porcine pancreatic phospholipase A2 complexed with micelles and a competitive inhibitor."
      van den Berg B. , Tessari M. , Boelens R. , Dijkman R. , Kaptein R. , de Haas G.H. , Verheij H.M.
      J. Biomol. NMR5:110-121(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
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